Table 2.
Comparisons of frequencies of blood hemoglobin, iron, vitamin B12, and folic acid deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody (GPCA) positivity between 68 burning mouth syndrome (BMS) patients with microcytosis (MCV < 80 fL) or 816 BMS patients without microcytosis and 442 healthy control subjects as well as between 68 BMS patients with microcytosis and 816 BMS patients without microcytosis.
| Group | Patient number (%) |
|||||
|---|---|---|---|---|---|---|
| Hemoglobin deficiency (Men < 13 g/dL, women < 12 g/dL) | Iron deficiency (<60 μg/dL) | Vitamin B12 deficiency (<200 pg/mL) | Folic acid deficiency (<4 ng/mL) | Hyperhomocysteinemia (>12.3 μM) | GPCA positivity | |
| BMS patients with microcytosis (n = 68) | 50 (73.5) | 30 (44.1) | 3 (4.4) | 2 (2.9) | 9 (13.2) | 7 (10.3) |
| aP-value | <0.001 | <0.001 | <0.001 | 0.010 | <0.001 | <0.001 |
| bP-value | <0.001 | <0.001 | 0.873 | 0.974 | 0.252 | 0.734 |
| BMS patients without microcytosis (n = 816) | 125 (15.3) | 113 (13.8) | 39 (4.8) | 18 (2.2) | 161 (19.7) | 102 (12.5) |
| aP-value | <0.001 | <0.001 | <0.001 | 0.004 | <0.001 | <0.001 |
| Healthy control subjects (n = 442) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 11 (2.5) | 8 (1.8) |
Comparisons of frequencies of parameters between 68 BMS patients with microcytosis or 816 BMS patients without microcytosis and 442 healthy control subjects by chi-square or Fisher's exact test, where appropriate.
Comparisons of frequencies of parameters between 68 BMS patients with microcytosis and 816 BMS patients without microcytosis by chi-square or Fisher's exact test, where appropriate.