Table 4.

Targets conserved in human cells not previous associated with nitrogen signalling. A list of human orthologues of the new targets of nitrogen signalling. GO-term mapping indicated the biological process regulated by the individual proteins.

novel nitrogen-regulated proteins—human orthologues
RNA metabolic processes (including: ribosome biogenesis, splicing, transcription, RNA catabolic process)
ABT1 CNOT1 CTNNBL1 CTR9 DDX17 DDX49 ESF1 IVL MED11 MTREX NIFK PLRG1 PPP2R2A RBM22 RNF10 RPAP1 RPL28 RPL35A RPS10 SCAF8 SREBF1 SRSF2 TAF10 TAF2 TAF9B THOC2 TRPT1 TTF1 UTP3
transport (including vesicle-mediated transport, transmembrane transport)
ABCB1 ARG1 ARID1A ATP13A1 ATP8A1 BIN1 BMP2 K CANX ESYT1 HID1 MAPK14 PDPK1 PSMD11 PSTPIP1 TAF7 TBC1D22A TRAPPC9 TTC17 WAS
chromosome organization
ARID1A CDC45 MORF4 SETD6 SIRT2 TAF7 USP7
lipid metabolic process
CERS2 ESYT1 GPCPD1 ORMDL1 PPM1 L
signal transduction
PPML1 PPP1R2 SUB1 URI1 ZNF622
autophagy
ATP6V1G1 CAMKK2 HSP90AA1 TSC2
mitochondrial ATP synthesis-coupled proton transport
ATP5ME
electron transfer activity
CIAPIN1
FAD biosynthetic process
FLAD1
protein folding
HSPA14
arginine biosynthetic process via ornithine
ASL