Table 5.

Targets conserved in human cells not previous associated with both nitrogen and Torin1-regulated signalling. A list of human orthologues of the new targets of nitrogen and Torin1 signalling. GO-term mapping indicated the biological process regulated by the individual proteins.

novel nitrogen and Torin1-regulated proteins—human orthologues
RNA metabolic processes(including: splicing, ribosomal protein, RNA stability)
DYRK1A RPS3A SCAF8 SNW1 SRSF5 TCF25
translation
EIF2B5 ETF1 CNOT7 SAMD4B UPF1
regulation of DNA repair
Trip12
vitamin metabolic process
GCH1
signal transduction
PPP2R5A
autophagy
NSFL1C
haem biosynthetic pathway
ALAS1
polarized cell growth
LRRC57
amino acid metabolic process (serine)
PHGDH