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. 2021 Apr 7;21:360. doi: 10.1186/s12885-021-08128-5

Table 4.

Toxicities of induction chemotherapy with TPF in patients treated for locally advanced head and neck cancer. Toxicity was assessed according to CTCAE classification V4.0

Grade ≥ 3 Grade 4 Grade 5
Anemia 16 (14%) 0 (0%) 0 (0%)
Neutropenia 39 (35%) 32 (34%) 2 (2%)
Febrile neutropenia 30 (27%) 1 (1%) 5 (6%)
Thrombocytopenia 7 (6%) 1 (1%) 1 (1%)
Nausea/Vomiting 24 (22%) 2 (3%) 0 (0%)
Mucositis 20 (18%) 1 (2%) 0 (0%)
Diarrhea 19 (17%) 0 (0%) 0 (0%)
Nephrotoxicity 0 (0%) 0 (0%) 0 (0%)
Digestive hemorrhage 6 (5%) 1 (1%) 1 (1%)