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. 2021 Apr 6;12:229. doi: 10.1186/s13287-021-02295-9

Table 3.

Azoospermia treated with mesenchymal stromal/stem cells in in vivo model studies

Source Transplantation Donor species Therapeutics Recipient species Modeling References
Adipose tissue Allotransplant Hamster Cell Hamster Busulfan [121]
Adipose tissue Allotransplant Mouse

Cell

Exosome

Mouse Busulfan [122]
Adipose tissue Allotransplant Rat Cell Rat Busulfan [70, 123, 124]
Adipose tissue Allotransplant Rat Cell Rat Cisplatin [125]
Adipose tissue Xenotransplant Human Cell Rat Torsion [126]
Amnion Allotransplant Mouse Cell Mouse Busulfan [127]
Bone marrow Allotransplant Guinea pig Cell Guinea pig Busulfan [128]
Bone marrow Allotransplant Hamster Cell Hamster Busulfan [129]
Bone marrow Allotransplant Mouse Cell Mouse Busulfan [130, 131]
Bone marrow Allotransplant Mouse

Cell

Exosome

Mouse Busulfan [122]
Bone marrow Allotransplant Mouse Cell Mouse Cisplatin [132]
Bone marrow Allotransplant Rat Cell Rat Busulfan [87, 89, 133138]
Bone marrow Allotransplant Rat Cell Rat Doxorubicin [139]
Bone marrow Allotransplant Rat Cell Rat Lead nitrate [140]
Bone marrow Allotransplant Rat Cell Rat Torsion [141]
Bone marrow Xenotransplant Goat Cell Mouse Busulfan [142]
Umbilical cord Xenotransplant Human Cell Mouse Busulfan [143145]
Urine Allotransplant Mouse

Cell

Exosome

Mouse Busulfan [146]