Table 4.
Clinical trials on mesenchymal stromal/stem cells-based therapy for female and male reproductive diseases (U. S. National Library of Medicine)
| Sex | Disease/syndrome | Phase | Date | Country | Source | Transplantation | Stage | CT code |
|---|---|---|---|---|---|---|---|---|
| Female | Atrophic endometrium | 2 | 2019 | Russia | Bone marrow | Autotransplant | Completed | NCT03166189 |
| Female | Fistula vagina | 1 | 2020 | United States | ND | Autotransplant | Completed | NCT03220243 |
| Female |
Intrauterine adhesions Endometrial dysplasia |
4 | 2014 | China | Bone marrow | Autotransplant | ND | NCT02204358 |
| Female | Intrauterine adhesions | ND | 2014 | China | Umbilical cord | Allotransplant | Completed | NCT02313415 |
| Female | Intraventricular hemorrhage | 2 | 2017 | Korea | Umbilical cord | Allotransplant | Recruiting | NCT02890953 |
| Female | Ovarian cancer | 1 | 2019 | United States | ND | Autotransplant | Completed | NCT02530047 |
| Female | Ovarian disease | 1&2 | 2015 | Jordan | Bone marrow | Autotransplant | Active | NCT03069209 |
| Female | Premature ovarian failure | 1&2 | 2018 | China | Umbilical cord | Allotransplant | Completed | NCT02644447 |
| Female | Premature ovarian failure | 1&2 | 2014 | Egypt | Bone marrow | Autotransplant | ND | NCT02696889 |
| Female | Premature ovarian failure | ND | 2016 | United States | Bone marrow | Autotransplant | Active | NCT02696889 |
| Female | Thin endometrium | 1 | 2018 | China | Umbilical cord | Allotransplant | Recruiting | NCT03592849 |
| Female | Thin endometrium | 1 | 2020 | Indonesia | Endometrium | Autotransplant | Recruiting | NCT04676269 |
| Female | Uterine scar | 2 | 2020 | China | Umbilical cord | Allotransplant | Recruiting | NCT02968459 |
| Female | Uterine scar | 1 | 2020 | China | Umbilical cord | Allotransplant | Recruiting | NCT03181087 |
| Female | Uterus injury | 2 | 2020 | China | Umbilical cord | Allotransplant | Recruiting | NCT03386708 |
| Male | Azoospermia | ND | 2015 | Egypt | Bone marrow | Autotransplant | Completed | NCT02414295 |
| Male | Azoospermia | 1&2 | 2014 | Egypt | Bone marrow | Autotransplant | ND | NCT02025270 |
| Male | Azoospermia | ND | 2013 | Egypt | Bone marrow | Autotransplant | Recruiting | NCT02008799 |
| Male | Azoospermia | 1&2 | 2014 | Egypt | Bone marrow | Autotransplant | Recruiting | NCT02041910 |
| Male | Azoospermia | 1&2 | 2015 | Jordan | Bone marrow | Autotransplant | Recruiting | NCT02641769 |
| Male |
Azoospermia Oligospermia |
2 | 2018 | Russia | Adipose tissue | Autotransplant | Recruiting | NCT03762967 |
| Male | Erectile dysfunction | 1 | 2018 | Jordan | Wharton’s Jelly | Allotransplant | Completed | NCT02945449 |
| Male | Erectile dysfunction | 1&2 | 2019 | Jordan | Wharton’s Jelly | Allotransplant | Completed | NCT03751735 |
| Male | Erectile dysfunction | 1 | 2018 | Korea | Bone marrow | Autotransplant | Completed | NCT02344849 |
| Male | Erectile dysfunction | 2 | 2020 | Korea | Bone marrow | Autotransplant | Recruiting | NCT04594850 |
ND no data