Table 1.
Baseline characteristics of participants in the discovery set and validation set
| Variables | Discovery set | Validation set | ||||||
|---|---|---|---|---|---|---|---|---|
| Controls (n = 292) | Cases (n = 292) | p a) | FDR a) | Controls (n = 208) | Cases (n = 208) | p a) | FDR a) | |
| Age (years) | 62.38 ± 7.05 | 62.34 ± 7.10 | 0.993 | 1.000 | 62.52 ± 7.44 | 62.47 ± 7.46 | 0.946 | 1.000 |
| Men sex, No. (%) | 47.3% | 47.3% | 1.000 | 1.000 | 40.9% | 40.9% | 1.000 | 1.000 |
| BMI (kg m−2) | 24.16 ± 3.31 | 25.96 ± 3.65 | <0.001 | <0.001 | 23.68 ± 3.02 | 25.64 ± 3.09 | <0.001 | <0.001 |
| Smoking status, No. (%) | ||||||||
| Current smoker | 24.8% | 20.6% | 0.400 | 23.2% | 18.9% | 0.450 | ||
| Former smoker | 9.7% | 11.3% | 0.486 | 6.3% | 7.8% | 0.679 | ||
| Never smoker | 65.5% | 68.0% | 70.5% | 73.3% | ||||
| Drinking status, No. (%) | ||||||||
| Current drinker | 27.1% | 26.7% | 0.768 | 22.6% | 19.2% | 0.322 | ||
| Former drinker | 3.4% | 5.5% | 0.870 | 5.8% | 4.8% | 0.548 | ||
| Never drinker | 69.5% | 67.8% | 71.6% | 76.0% | ||||
| Physical activity, No. (%) | 90.8% | 87.3% | 0.186 | 0.263 | 88.5% | 87.0% | 0.654 | 0.833 |
| Systolic blood pressure (mmHg) | 127.00 ± 18.67 | 130.64 ± 17.93 | 0.015 | 0.028 | 127.07 ± 17.27 | 129.54 ± 18.54 | 0.196 | 0.417 |
| Diastolic blood pressure (mmHg) | 76.48 ± 11.07 | 79.04 ± 11.08 | 0.010 | 0.021 | 77.30 ± 10.19 | 77.91 ± 10.56 | 0.480 | 0.679 |
| HDL cholesterol (mmol L−1) | 1.49 ± 0.45 | 1.40 ± 0.49 | 0.002 | 0.004 | 1.46 ± 0.43 | 1.38 ± 0.39 | 0.037 | 0.089 |
| LDL cholesterol (mmol L−1) | 3.01 ± 0.79 | 3.05 ± 0.72 | 0.333 | 0.436 | 3.01 ± 0.78 | 2.99 ± 0.74 | 0.909 | 1.000 |
| Triglycerides (mmol L−1) | 1.29 ± 0.70 | 1.64 ± 0.93 | <0.001 | <0.001 | 1.36 ± 0.83 | 1.67 ± 1.00 | <0.001 | <0.001 |
| Fasting glucose (mmol L−1) | 5.53 ± 0.55 | 5.99 ± 0.61 | <0.001 | <0.001 | 5.51 ± 0.58 | 6.02 ± 0.56 | <0.001 | <0.001 |
a)
Values of p and FDR were calculated by nonparametric tests.