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Plasmodium infection suppresses the activation of the PI3K/Akt/GSK-3β signalling pathway. (A) Western blot analysis of PI3K, p-PI3K, Akt, p-Akt, GSK-3β and p-GSK-3β in the Hep and Hep + Py groups. The ratio of (B) p-PI3K/PI3K, (C) p-Akt/Akt and (D) p-GSK-3β/ GSK-3β in the two groups. Data are presented as the mean ± SD. *P<0.05. Hep, mice inoculated with Hepa1-6 cells; Py, Plasmodium yoelii 17XNL; p-, phosphorylated.
