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. 2021 Apr 6;9:60. doi: 10.1186/s40478-021-01161-2

Table 2.

Experimental timeline

Group # Tests Sample size (n) for shams and rmTBI mice at each time point Time points
I mTBI kinematics 4 control
II Western Blot 6 sham (48 h after the last sham procedure) and 6 rmTBI 8 h, 48 h, 1 w and 20 w
IIa Western blot (Naïves and Shams) 4 naïve, 5 sham (8 h after the last sham procedure) and 5 shams (48 h after the last sham procedure) 8 h, 48 h
III DTI and MRS/ IHC/ Metabolomics 12 control and 12 rmTBI for MRS, DTI and metabolomics; 6 control and 6 rmTBI for IHC; 48 h, 1 w, 4 w and 10 w
IV 5-CSRTT 8 sham, 10 rmTBI 2 w, 6 w and 10 w
EM 6 sham, 6 rmTBI 20 w
V PVD 14 sham, 15 rmTBI 2 w, 6 w and 10 w
MWM 13 sham, 15 rmTBI 16 w