Table 3.
Expression of target genes in patients with clear-cell renal-cell carcinoma characterized by high/low visceral adiposity
| Low visceral adiposity | High visceral adiposity | Pa | Pb | |
|---|---|---|---|---|
| mRNA expression (× 100) | (N = 100) | (N = 100) | ||
| Frozen tissue | ||||
| FOXC2 | 17.011 ± 33.556 | 7.896 ± 14.304 | 0.014 | 0.003 |
| CLIP4 | 17.158 ± 32.455 | 9.365 ± 12.712 | 0.027 | 0.121 |
| PBRM1 | 8.950 ± 11.257 | 7.032 ± 8.787 | 0.181 | 0.249 |
| SETD2 | 1.476 ± 2.153 | 2.077 ± 2.316 | 0.059 | 0.759 |
| BAP1 | 18.530 ± 59.910 | 1.649 ± 6.515 | 0.006 | 0.201 |
| KDM5C | 1.744 ± 2.704 | 1.954 ± 5.187 | 0.720 | 0.508 |
| AQP1 | 1.283 ± 1.486 | 1.958 ± 0.981 | < 0.001 | 0.008 |
| DDX11 | 10.196 ± 10.477 | 1.890 ± 2.875 | < 0.001 | < 0.001 |
| BAIAP2L1 | 3.007 ± 4.574 | 2.403 ± 3.139 | 0.277 | 0.051 |
| TMEM38B | 4.627 ± 7.711 | 7.055 ± 12.656 | 0.103 | 0.382 |
| Plasma | ||||
| FOXC2 | 16.708 ± 11.659 | 16.235 ± 8.215 | 0.740 | 0.705 |
| CLIP4 | 16.848 ± 22.763 | 17.631 ± 22.080 | 0.805 | 0.895 |
| PBRM1 | 2.452 ± 2.180 | 5.751 ± 41.896 | 0.417 | 0.099 |
| SETD2 | 1.339 ± 1.690 | 2.346 ± 1.388 | < 0.001 | 0.512 |
| BAP1 | 98.325 ± 357.418 | 43.885 ± 244.658 | 0.210 | 0.633 |
| KDM5C | 13.468 ± 19.377 | 6.992 ± 9.286 | 0.003 | 0.776 |
| AQP1 | 12.095 ± 19.380 | 8.017 ± 16.235 | 0.108 | 0.286 |
| DDX11 | 5.484 ± 11.271 | 2.641 ± 2.657 | 0.016 | 0.081 |
| BAIAP2L1 | 9.706 ± 15.835 | 4.965 ± 11.904 | 0.018 | 0.140 |
| TMEM38B | 17.087 ± 21.024 | 22.035 ± 33.570 | 0.213 | 0.523 |
Data are shown as the means ± standard deviations
aP values determined using Student’s t-test for univariate analysis
bP values determined using logistic regression for multivariate analysis