Table 4.
Predictors of high visceral adiposity in clinical T1a clear-cell renal-cell carcinoma
| Univariate | Multivariate | |||
|---|---|---|---|---|
| OR (95% CI) | Pa | OR (95% CI) | Pb | |
| Clinical parameters | ||||
| Gender (reference male) | 0.055 (0.019–0.162) | < 0.001 | 0.000 (0.000–0.000) | 0.997 |
| BMI (kg/m2) | 1.496 (1.311–1.707) | < 0.001 | 1.148 (0.957–1.376) | 0.138 |
| Hypercholesterolemia (vs. none) | 3.273 (1.018–10.523) | 0.047 | 3.042 × e10 | 0.996 |
| Smoking (vs. never) | ||||
| Former | 3.353 (1.653–6.803) | 0.001 | 0.284 (0.080–1.007) | 0.051 |
| Current | 16.185 (6.650–39.392) | < 0.001 | 2.406 (0.606–9.545) | 0.212 |
| Alcohol (vs. never) | ||||
| Former | 4.747 (2.055–10.964) | < 0.001 | 1.854 (0.383–8.965) | 0.443 |
| Current | 3.048 (1.575–5.895) | 0.001 | 0.374 (0.109–1.290) | 0.119 |
| mRNA expression levels | ||||
| DDX11 (frozen tissue) | 0.785 (0.726–0.850) | < 0.001 | 0.816 (0.706–0.943) | 0.006 |
|
ISUP nuclear grade (reference low-grade) |
0.070 (0.034–0.142) | < 0.001 | 0.245 (0.061–0.974) | 0.046 |
aP values determined using logistic regression for univariate analysis
bP values determined using logistic regression for multivariate analysis. BMI body mass index