Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 7;86:103656. doi: 10.1016/j.etap.2021.103656

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Author(s)

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

PMC Copyright notice

Fig. 3 — Nicotine vapor inhalation alters nicotinic receptor subunit mRNA expression in lungs. Following treatment, expression of the nicotinic acetylcholine receptor (nAChR) subunits were examined in lung tissue. (a) Males exposed to either vehicle vapor or nicotine vapor exhibited a significant decrease in expression of α5 nAChR mRNA compared to the control condition. (b) In females, vehicle vapor or nicotine vapor exposure decreased expression of α5 nAChR mRNA in lung tissue compared to the control condition. (c) In males, no differences were found in the expression of α7 mRNA among groups. (d) In females, α7 mRNA exhibited no differences in expression following vapor exposure. Individual data points are represented on each graph, and graph bars express as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.0001 vs control group.