Figure 6.

K562/DOXO cells after 15-min incubation with peroxidase-containing liposomes. (A) The cells show a normal ultrastructure and one of them (center) shows a cluster of membrane-bound, electron-dense particles, identified as liposomes, opposed to the plasma membrane. (B) Detail of the liposomes shown in (A), some of which are attached to the plasma membrane; mitochondria still show a normal appearance. (C) Cells showing moderate cytoplasmic vacuolation (see insert) and electron-dense particles corresponding to liposomes (arrowheads). (D) Detail of the cell in (C).