Table 3. Diagnostic accuracy of UGAP and CAP for the diagnosis of steatosis grade.
≥S1 (95% CI) | ≥S2 (95% CI) | S3 (95% CI) | ||||
---|---|---|---|---|---|---|
UGAP | CAP | UGAP | CAP | UGAP | CAP | |
AUROC | 0.891 * (0.837–0.945) | 0.829 (0.775–0.903) | 0.909 * (0.869–0.949) | 0.832 (0.782–0.902) | 0.924 ** (0.877–0.972) | 0.801 (0.717–0.886) |
Cut-off value | 0.493 | 241 | 0.654 | 276 | 0.691 | 300 |
Sensitivity | 0.791 (0.729–0.842) | 0.627 (0.558–0.691) | 0.842 (0.723–0.916) | 0.807 (0.684–0.890) | 0.882 (0.642–0.977) | 0.765 (0.521–0.908) |
Specificity | 0.900 (0.684–0.982) | 0.950 (0.743–1.000) | 0.866 (0.804–0.910) | 0.774 (0.704–0.832) | 0.833 (0.776–0.878) | 0.721 (0.655–0.778) |
PPV | 0.988 (0.970–1.000) | 0.992 (0.977–1.000) | 0.686 (0.577–0.794) | 0.554 (0.447–0.661) | 0.306 (0.177–0.435) | 0.186 (0.095–0.277) |
NPV | 0.300 (0.184–0.416) | 0.202 (0.121–0.283) | 0.940 (0.903–0.978) | 0.920 (0.875–0.965) | 0.988 (0.972–1.000) | 0.974 (0.948–0.999) |
LR+ | 7.910 (2.120–29.515) | 12.537 (1.850–84.946) | 6.278 (4.188–9.410) | 3.577 (2.622–4.880) | 5.294 (3.721–7.532) | 2.737 (1.941–3.859) |
LR- | 0.232 (0.171–0.315) | 0.393 (0.320–0.482) | 0.182 (0.100–0.333) | 0.249 (0.146–0.426) | 0.141 (0.038–0.520) | 0.327 (0.138–0.773) |
AUROC, area under receiver the operating curve; CAP, controlled attenuation parameter; CI: Confidence interval; LR+, positive likelihood ratio; LR–, negative likelihood ratio; NPV, negative predictive value; PPV, positive predictive value; UGAP, ultrasound-guided attenuation parameter.
* p < 0.05 (compared with CAP).
** p < 0.01 (compared with CAP).