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. 2021 Apr 7;16(4):e0249791. doi: 10.1371/journal.pone.0249791

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© 2021 Sweeney et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — 168 serum samples from individuals with confirmed SARS-CoV-2 infection were tested for the presence of antibody by ELISA to the full spike (S), receptor binding domain (RBD) and nucleocapsid (N), and by SureScreen lateral flow immunoassay. Detection of IgG is shown in the top panel, and IgM in the bottom panel. Samples are arranged according to days post onset of symptoms, ranging from 14 to 40 days. Results are displayed as a heatmap, with white indicating a negative result, and gradations of orange indicating the magnitude of response detected.