Table 2. Comparative data between patients with and without native lung complications following single lung transplantation (overall group).
| NATIVE LUNG COMPLICATIONS | NO (n = 112) | YES (n = 49) | p | ||
|---|---|---|---|---|---|
| 95% CI | 95% CI | ||||
| Recipient age (years) | 57±7 | 58±7 | 0.86 | ||
| Recipient gender: | 0.48 | ||||
| Male | 80 (71) | 38 (77) | |||
| Female | 32 (29) | 11 (23) | |||
| Preop. Steroids | 20 (19) | 12–26 | 14 (28) | 16–40 | 0.14 |
| Ischemic time (min) | 307±57 | 297–317 | 295±53 | 281–309 | 0.57 |
| CPB / ECMO | 14 (12) | 6–18 | 2 (4) | 0–8 | 0.05 |
| ICU stay (days) | 10±17 | 7–13 | 33±96 | 7–59 | <0.001 |
| Postop. Intubation (h) | 41±85 | 26–56 | 99±318 | 54–144 | 0.006 |
| Hospital stay (days) | 30±24 | 26–34 | 45±34 | 36–54 | 0.03 |
| PaO2/FiO2 24h postop. (mm Hg) | 345±146 | 318–372 | 316±182 | 265–367 | 0.35 |
| Comorbidities | 39 (35) | 26–44 | 24 (49) | 35–63 | 0.04 |
| Native lung perfusion (%) | 52±9 | 51–53 | 48±13 | 45–51 | 0.29 |
| Native lung side (left/right) | 30/82 (26/74) | 18-34/66-82 | 10/39 (20/80) | 9-31/69-91 | 0.29 |
| CLAD | 4 (3) | 0–6 | 5 (10) | 2–18 | 0.12 |
| Pre-transplant status | |||||
| Airway colonizations | 4 (3) | 0–6 | 15 (30) | 18–42 | <0.001 |
| Bullae | 36 (32) | 24–40 | 30 (61) | 48–74 | 0.003 |
| Granulomas | 7 (6) | 2–10 | 7 (14) | 5–23 | 0.13 |
| Hyperinflation | 0 | 3 (6) | 0–12 | 0.03 | |
| Mechanical ventilation | 2 (2) | 0–4 | 0 | 0.44 | |
| LVRS | 0 | 3 (6) | 0–12 | 0.03 | |
| 30-day mortality | 16 (14) | 8–20 | 1 (2) | 0–4 | 0.008 |
CPB: cardiopulmonary bypass; CLAD: chronic lung allograft dysfunction; ECMO: extracorporeal membrane oxygenation; LVRS: lung volume reduction surgery. Quantitative variables are expressed as mean ± standard deviation. Qualitative variables are expressed as counts and proportions within each column, in parenthesis.