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. Author manuscript; available in PMC: 2021 Apr 7.
Published in final edited form as: J Comp Neurol. 2018 Dec 4;527(13):2122–2145. doi: 10.1002/cne.24555

Figure 11. Plaque distribution across cortical layers differs between mouse lines.

Figure 11.

Images showing plaques in the parietal cortex of 19-month-old APP/PS1 (a), Tg2576 (b), and hAPP-J20 (c) mice. Approximate layer boundaries are indicated in text to the right of each image (wm = white matter). Scale = 500 μm. The relative plaque density in each cortical layer across the entire isocortex is plotted separately for APP/PS1 (b), Tg2576 (d), and hAPP-J20 (f) mouse lines. Box plots show median and IQR with whiskers extending up to 1.5 times the IQR. Outliers are plotted as individual points.