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. Author manuscript; available in PMC: 2021 Apr 7.
Published in final edited form as: J Comp Neurol. 2018 Dec 4;527(13):2122–2145. doi: 10.1002/cne.24555

Table 1.

Experimental Dataset

Mouse Line Promoter 5 mo
(M/F)		 7 mo
(M/F)		 9 mo
(M/F)		 13 mo
(M/F)		 19 mo
(M/F)
APP/PS1 (APP+/−) moPrP 6 (4/2) 13 (9/4) 6 (3/3) 39 (36/3) 9 (7/2)
hAPP-J20 (APP+/−) PDGF-β 4 (2/2) 3 (2/1) 5 (2/3) 11 (6/5) 3 (0/3)
Tg2576 (APP+/−) haPrP 3 (0/3) 5 (0/5) 4 (0/4)
Controls
APP/PS1 (APP−/−) 2 (2/0) 11 (7/4) 2 (0/2)
hAPP-J20 (APP−/−) 2 (1/1) 17 (9/8) 1 (0/1)

Transgenic mouse lines used in this study and the number of experimental animals in each group. Numbers in parentheses indicate the number of males and females in each mouse line/age group combination. The promoter used to drive APP expression for each transgenic line is indicated in the table. Control mice were APP−/− littermates of experimental mice.