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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Toxicol Sci. 2020 Sep 1;177(1):11–26. doi: 10.1093/toxsci/kfaa101

Figure 5. Distribution of ToxPi scores across tumorigenic and nontumorigenic chemicals.

Figure 5.

Distribution of ToxPi scores between tumorigenic and nontumorigenic chem-dose-times in the TG-GATES study. ToxPi scores were derived from the -Log(p-value)s of the 6 biomarkers compared to each bioset. (Top) Distribution of scores. The optimal ROC threshold is indicated. (Bottom) Heatmap of -Log(p-value)s of the biomarkers. The blue line separates the tumorigenic and nontumorigenic exposure conditions.