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. 2021 Mar 8;5:2399202620980303. doi: 10.1177/2399202620980303

Table 2.

Average annual costs, investments, and returns to test amoxicillin quality in Kenya.

HPLC (reference) Expedited HPLC PADs/aPADs
Costs
 Sampling, screening, testing, & removal costs $9,153 $9,153 $6,120
 Incremental investment $3,033 $3,033 $0
Benefits
 Treatment costs $13,368,329 $13,206,543 $12,937,990
 Productivity losses: short-term $5,364,369 $5,289,872 $5,166,347
  Long-term $308,913,977 $303,549,139 $294,656,953
 Incremental return
  Excluding productivity $161,787 $430,339
  Including productivity $5,601,122 $14,855,385
Cost per benefit
 Number of child pneumonia deaths 12,707 12,486 12,120
 Deaths averted 221 586
 Cost per death averted $41.42 $10.44
 Number of SF treatments received 25,075 21,339 15,144
 SF treatments averted 3,736 9,931
 Cost per SF treatment averted $2.45 $0.62
 SF treatments removed from market 4,685 6,770 13,628
 Cost per SF treatment removed $1.95 $1.35 $0.45

HPLC: high-performance liquid chromatography; PADs/aPADs: paper analytical devices/antibiotic paper analytical devices; SF: substandard or falsified.

The table presents annual average costs over 3 year model runs. Across all scenarios, the numbers of overall treatments (SF treatments + legitimate treatments) are kept constant. The PADs/aPADs with HPLC scenario draws three different samples over 3 years, and is thus is able to detect and remove more SF amoxicillin compared to other scenarios.