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. 2021 Apr 8;112:104889. doi: 10.1016/j.bioorg.2021.104889

Fig. 2.

Fig. 2

Percent inhibition of Ebselen 1a-j, Ebsulfur 2a-q and compounds 311 (50 µM) against Mpro determined by FRET assays. Mca–AVLQSGFRK(Dnp)K (20 µM) was used as the fluorescent substrate, and the enzymatic concentration was 0.2 µM. Ebselen 1j was used as the positive control and 0.5% DMSO was used as the negative control.