Table 2.
Distribution and characteristics of studies on ESBL-PE in Ethiopia (2005–2019).
| Authors and reference | Study area | Region | Study design | Population |
|---|---|---|---|---|
| Beyene et al. [20] | Addis Ababa | Central Ethiopia | MC-cross-sectional | Children with febrile illness and diarrheal diseases |
| Alemu [24] | Addis Ababa | Central Ethiopia | Cross-sectional | <5 Children suspected for colonization/carriage |
| Legese et al. [6] | Addis Ababa | Central Ethiopia | Cross-sectional | Children suspected of septicemia and UTIs |
| Teklu et al. [7] | Addis Ababa | Central Ethiopia | MC-cross-sectional | Patients |
| Desta et al. [12] | Addis Ababa | Central Ethiopia | Cross-sectional | Hospitalized patients with gastrointestinal colonization |
| Beyene et al. [25] | Addis Ababa | Central Ethiopia | Cross-sectional | Patients |
| Kind [26] | Addis Ababa | Central Ethiopia | Cross-sectional | Patients |
| Mitiku [27] | Addis Ababa | Central Ethiopia | Cross-sectional | Septicemia suspected |
| Moges et al. [28] | Bahir Dar | Amhara | Cross-sectional | All patients suspected of UTI and other infections |
| Eshetie et al. [23] | Gondar | Amhara | Cross-sectional | UTI suspected patients |
| Mulualem et al. [29] | Jimma | Oromia | Cross-sectional | Patients suspected of UTI and GIT |
| Abayneh et al. [30] | Jimma | Oromia | Cross-sectional | Patients suspected of community-onset UTI |
| Gashaw et al. [31] | Jimma | Oromia | Cross-sectional | Patients suspected of HAIs |
| Zeynudin et al. [22] | Jimma | Oromia | Cross-sectional | Patients suspected of UTI wound infections |
| Siraj et al. [11] | Jimma | Oromia | MC-cross-sectional | Patients suspected of UTI, wound infections, GIT, and respiratory infections |
| Mulisa et al. [32] | Adama | Oromia | Cross-sectional | Patients |
| Gebremariam et al. [33] | Mekelle | Tigray | Cross-sectional | University students |
| Seid and Asrat [21] | Harrar | Harrari | MC-cross-sectional | Admitted patients |
MC, multicentre; UTI, urinary tract infection; GIT, gastrointestinal tract infection; HAIs, hospital-acquired infections In the total of 18 included studies, a total of 1191 bacterial isolates were recovered from 7919 various clinical samples being E. coli and K. pneumoniae were the most studied isolates of ESBL-PE accounting for 50% followed by the combination of other species such as Proteus spp., K. oxytoca, E. cloacae, Citrobacter spp., E. aerogenes, Salmonella spp., and C. freundii with E. coli and K. pneumoniae yielding 38.9% prevalence.