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The IC50 value of 1,6,8-trihydroxyxanthone (HX1) compound and chloroquine on the formation of the β-hematin using method of HPIA.
| Compounds | Concentration (mM) | β-Hematin (mM) | Inhibition of β-hematin (%) | IC50 (mM) |
|---|---|---|---|---|
| HX1 | 20.475 | 9.684 | 91.171 | 2.854 |
| 10.238 | 14.376 | 86.893 | ||
| 5.119 | 54.448 | 50.359 | ||
| 2.580 | 55.776 | 49.149 | ||
| 1.269 | 72.500 | 33.901 | ||
|
| ||||
| Chloroquine | 9.692 | 12.500 | 88.604 | 1.478 |
| 4.846 | 22.040 | 79.906 | ||
| 2.423 | 47.845 | 56.379 | ||
| 1.221 | 57.787 | 47.315 | ||
| 0.601 | 77.787 | 29.080 | ||
