Table 4.
The IC50 values of hydroxyxanthone compounds on Vero cell after 24 hours incubation using the MTT assay method.
| Compounds | Concentration (μM) | Vero cell growth inhibition (%) after 24 hours incubation | IC50 (µM) |
|
| |||
| HX1 | 8190.01 | 89.43 ± 1.90 | 3394.90 ± 435.44 |
| 4095.00 | 45.86 ± 5.51 | ||
| 2047.50 | 27.96 ± 5.69 | ||
| 1023.75 | 15.89 ± 8.24 | ||
| 511.88 | −4.13 ± 8.21 | ||
| 255.94 | −50.32 ± 17.18 | ||
|
| |||
| HX2 | 1734.91 | 86.09 | 308.32 |
| 867.45 | 67.03 | ||
| 433.73 | 59.75 | ||
| 216.86 | 38.93 | ||
| 108.26 | 31.75 | ||
| 54.13 | 15.63 | ||
|
| |||
| HX3 | 2047.50 | 88.86 | 224.45 |
| 1023.75 | 79.92 | ||
| 511.88 | 68.04 | ||
| 255.94 | 55.70 | ||
| 127.76 | 39.58 | ||
| 63.88 | 20.70 | ||
|
| |||
| HX4 | 2027.14 | 89.96 | 330.68 |
| 1013.57 | 68.87 | ||
| 506.78 | 54.41 | ||
| 253.39 | 43.17 | ||
| 126.49 | 32.49 | ||
| 63.25 | 19.04 | ||
|
| |||
| HX5 | 2064.07 | 88.76 | 417.57 |
| 1032.03 | 68.13 | ||
| 516.02 | 48.33 | ||
| 258.01 | 37.83 | ||
| 128.80 | 27.88 | ||
| 64.40 | −5.19 | ||