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The selectivity index (ratio IC50 on Vero cell/IC50 on plasmodium) of hydroxyxanthone compounds and chloroquine.
| Compounds | IC50 on Vero cell (μM) | Selectivity index | |
|---|---|---|---|
| 3D-7 | FCR-3 | ||
| HX1 | 3394.90 | 556.54 | 502.20 |
| HX2 | 308.32 | 4.30 | 3.77 |
| HX3 | 224.45 | 8.12 | 3.50 |
| HX4 | 330.68 | 3.88 | 3.68 |
| HX5 | 417.57 | 8.94 | 6.99 |
| Chloroquine | 2216.92 | 221692 | 20153.82 |
