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. Author manuscript; available in PMC: 2021 Apr 7.
Published in final edited form as: ACS Infect Dis. 2018 Jun 25;5(5):659–674. doi: 10.1021/acsinfecdis.8b00081

Figure 4. Mechanisms to eliminate cccDNA.

Figure 4.

Pre-existing cccDNA can be eliminated by killing of infected hepatocytes (A) or non-cytolytically cure of infected hepatocytes via three distinct mechanisms (B).