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Top panel, HBV transcriptional cis regulatory elements, ORFs, and transcripts are presented in reference to linear DNA longer than unit-length of HBV genome. Middle panel, the structure of HBV DNA double stranded linear (dsl) DNA genome is presented. Low panel, the structure of integrated HBV DNA is presented. Due to the processing of the dslDNA ends during integration, variable length of DNA sequences may be lost (dashed lines).
