Table 2.
Circadian-regulated genes (FDR-adjusted p < 0.01)a
| Gene | Baseline expression | Log2 fold change | p | FDR | Description |
|---|---|---|---|---|---|
| vri | 3724.50 | −4.6985 | 4.29E-106 | 3.89E-102 | core circadian clockb |
| tim | 5834.10 | −3.7979 | 4.29E-78 | 1.95E-74 | core circadian clockb |
| GstD3 | 1104.77 | 2.5973 | 3.46E-28 | 1.05E-24 | glutathione metabolismb |
| CG2016 | 281.15 | 2.9593 | 1.22E-22 | 2.77E-19 | hormone binding |
| CG33757 | 410.74 | 2.9298 | 1.03E-19 | 1.87E-16 | no functional information |
| Cyp4d21 | 4279.26 | −1.8094 | 7.21E-18 | 1.09E-14 | oxidation-reduction processb |
| Clk | 143.92 | 2.9383 | 2.18E-16 | 2.82E-13 | core circadian clockb |
| CG10026 | 352.82 | 2.3039 | 3.80E-15 | 4.31E-12 | lipid binding |
| Ugt35b | 46348.94 | 1.3358 | 3.54E-11 | 3.56E-08 | UDP glycosyl transferaseb |
| GstE9 | 1001.76 | 1.4003 | 2.71E-10 | 2.46E-07 | glutathione metabolismb |
| CG31324 | 749.19 | −1.6055 | 4.71E-09 | 3.88E-06 | no functional information |
| Pdh | 55.97 | 2.9461 | 7.75E-09 | 5.85E-06 | receptor dehydrogenaseb |
| CG6834 | 2496.64 | 1.1409 | 1.30E-08 | 9.04E-06 | no functional information |
| CG7208 | 108.72 | −2.2001 | 1.99E-08 | 1.29E-05 | no functional information |
| mt:lrRNA | 418.18 | 2.0580 | 1.64E-07 | 9.93E-05 | mitochondrial translation |
| CG15096 | 1139.97 | −1.1414 | 2.08E-07 | 1.14E-04 | transmembrane anion transport |
| slik | 449.97 | 1.3790 | 2.14E-07 | 1.14E-04 | cell proliferation |
| CG9815 | 39.03 | −3.1059 | 2.43E-07 | 1.23E-04 | no functional information |
| cu | 674.29 | −1.1606 | 3.45E-07 | 1.57E-04 | NADP metabolismb |
| zormin | 503.40 | 1.1680 | 3.29E-07 | 1.57E-04 | cytoskeletal structure |
| CG10513 | 326.16 | 1.2906 | 3.72E-07 | 1.61E-04 | no functional information |
| Ugt86De | 477.43 | 1.2370 | 5.25E-07 | 2.17E-04 | UDP glycosyl transferaseb |
| CG6484 | 322.18 | −1.2398 | 7.35E-07 | 2.90E-04 | glucose import |
| CheB93b | 215.37 | 1.7419 | 1.21E-06 | 4.56E-04 | pheromone detection |
| CG7149 | 1784.54 | 0.9488 | 1.49E-06 | 5.42E-04 | phosphotransferase |
| CG31100 | 1430.28 | −1.0624 | 2.34E-06 | 8.16E-04 | glucose import |
| CG10433 | 1716.02 | 1.0842 | 2.70E-06 | 9.06E-04 | female receptivity to mating |
| CG2930 | 545.58 | 1.0604 | 4.77E-06 | 1.55E-03 | transmembrane transport |
| CG6356 | 4808.16 | −1.4003 | 5.51E-06 | 1.72E-03 | transmembrane transport |
| CG33946 | 117.51 | 1.6102 | 5.89E-06 | 1.78E-03 | no functional information |
| wbl | 231.65 | 1.3672 | 6.67E-06 | 1.95E-03 | protein folding in ER |
| CG3625 | 6333.94 | 0.8930 | 7.49E-06 | 2.12E-03 | no functional information |
| CG31321 | 34.98 | 2.6316 | 8.08E-06 | 2.22E-03 | transmembrane transport |
| CG13841 | 243.03 | 1.4691 | 1.28E-05 | 3.42E-03 | no functional information |
| CG7724 | 912.70 | 0.9733 | 1.44E-05 | 3.74E-03 | oxidation-reduction process |
| Ugt35a | 303.93 | 1.2040 | 1.63E-05 | 4.10E-03 | UDP glycosyl transferaseb |
| CG1698 | 22.34 | 3.7173 | 1.72E-05 | 4.22E-03 | neurotransmitter transport |
| CG11951 | 39.60 | 2.5616 | 1.79E-05 | 4.26E-03 | proteolysis |
| mt:ND2 | 385.70 | 1.0282 | 1.84E-05 | 4.29E-03 | mitochondrial electron transport |
| CG6910 | 255.13 | 1.1671 | 2.27E-05 | 5.16E-03 | oxidation-reduction process |
| cwo | 1095.79 | −0.8935 | 2.82E-05 | 6.24E-03 | circadian regulation of gene expressionb |
ap, Unadjusted p value; FDR, p value adjusted for multiple comparisons.
bKnown clock-controlled genes (Claridge-Chang et al., 2001; McDonald and Rosbash, 2001) or genes annotated as circadian-related in FlyBase.