Table 8.
Enriched GO biological process terms after 12 h of Kir2.1 inductiona
| GO ID | Term | Annotated | Observed | Expected | Fisher's p |
|---|---|---|---|---|---|
| GO:0034330 | cell junction organization | 273 | 27 | 14 | 1.20E-03 |
| GO:0006887 | exocytosis | 75 | 11 | 4 | 1.80E-03 |
| GO:0016079 | synaptic vesicle exocytosis | 44 | 8 | 2 | 1.90E-03 |
| GO:0035295 | tube development | 550 | 45 | 29 | 2.00E-03 |
| GO:0065008 | regulation of biological quality | 888 | 66 | 47 | 2.20E-03 |
| GO:0060562 | epithelial tube morphogenesis | 373 | 33 | 20 | 2.40E-03 |
| GO:0007399 | nervous system development | 843 | 63 | 45 | 2.50E-03 |
| GO:0000209 | protein polyubiquitination | 58 | 9 | 3 | 3.20E-03 |
| GO:0035239 | tube morphogenesis | 400 | 34 | 21 | 3.90E-03 |
| GO:0007611 | learning or memory | 119 | 14 | 6 | 4.00E-03 |
| GO:0050890 | cognition | 119 | 14 | 6 | 4.00E-03 |
| GO:1901565 | organonitrogen compound catabolic process | 327 | 29 | 17 | 4.20E-03 |
| GO:0006836 | neurotransmitter transport | 95 | 12 | 5 | 4.20E-03 |
| GO:0010648 | negative regulation of cell communication | 241 | 23 | 13 | 4.30E-03 |
| GO:0023057 | negative regulation of signaling | 241 | 23 | 13 | 4.30E-03 |
| GO:0045055 | regulated exocytosis | 50 | 8 | 3 | 4.40E-03 |
| GO:0048519 | negative regulation of biological process | 1047 | 74 | 56 | 4.40E-03 |
| GO:0042391 | regulation of membrane potential | 51 | 8 | 3 | 5.00E-03 |
| GO:0048729 | tissue morphogenesis | 483 | 39 | 26 | 5.00E-03 |
| GO:0007610 | behavior | 377 | 32 | 20 | 5.20E-03 |
| GO:0007269 | neurotransmitter secretion | 74 | 10 | 4 | 5.40E-03 |
| GO:0099643 | signal release from synapse | 74 | 10 | 4 | 5.40E-03 |
| GO:0034329 | cell junction assembly | 176 | 18 | 9 | 5.40E-03 |
| GO:0007613 | memory | 86 | 11 | 5 | 5.50E-03 |
| GO:0051124 | synaptic growth at NMJ | 111 | 13 | 6 | 5.70E-03 |
| GO:0007416 | synapse assembly | 137 | 15 | 7 | 5.80E-03 |
| GO:0007528 | neuromuscular junction development | 138 | 15 | 7 | 6.20E-03 |
| GO:0060429 | epithelium development | 730 | 54 | 39 | 6.40E-03 |
| GO:0008582 | regulation of synaptic growth at NMJ | 88 | 11 | 5 | 6.50E-03 |
| GO:0050808 | synapse organization | 221 | 21 | 12 | 6.60E-03 |
| GO:0050803 | regulation of synapse structure or activity | 139 | 15 | 7 | 6.60E-03 |
| GO:0048523 | negative regulation of cellular process | 914 | 65 | 49 | 6.80E-03 |
| GO:0042752 | regulation of circadian rhythm | 65 | 9 | 3 | 6.90E-03 |
| GO:0048569 | postembryonic animal organ development | 371 | 31 | 20 | 7.40E-03 |
| GO:0007267 | cell-cell signaling | 326 | 28 | 17 | 7.50E-03 |
| GO:0009888 | tissue development | 786 | 57 | 42 | 7.70E-03 |
| GO:0099003 | vesicle-mediated transport in synapse | 78 | 10 | 4 | 7.80E-03 |
| GO:0099504 | synaptic vesicle cycle | 78 | 10 | 4 | 7.80E-03 |
| GO:0010646 | regulation of cell communication | 595 | 45 | 32 | 8.70E-03 |
| GO:0023051 | regulation of signaling | 595 | 45 | 32 | 8.70E-03 |
| GO:0007163 | establishment or maintenance of cell polarity | 171 | 17 | 9 | 9.00E-03 |
| GO:0015672 | monovalent inorganic cation transport | 92 | 11 | 5 | 9.10E-03 |
| GO:0030163 | protein catabolic process | 228 | 21 | 12 | 9.30E-03 |
| GO:0002009 | morphogenesis of an epithelium | 470 | 37 | 25 | 9.30E-03 |
| GO:0006508 | proteolysis | 471 | 37 | 25 | 9.60E-03 |
| GO:1904396 | regulation of NMJ development | 93 | 11 | 5 | 9.80E-03 |
| GO:0030100 | regulation of endocytosis | 46 | 7 | 2 | 1.00E-02 |
aAnnotated, number of genes in the universe attached to a GO term; Observed, number of differentially expressed genes (unadjusted p < 0.05) attached to a GO term; Expected, number of genes expected by chance to be attached to a GO term.