Table 2.

Univariate and multivariate linear regression models to assess cardiovascular determinants of performance in physical function tests

Variable	Outcome	Univariate model			Multivariate modela
		Participants	B (SE)	P Value	Participants	B (SE)	P Value	R2
Troponin I (ng/L)b	ISWT	111	− 39.84 (13.2)	< 0.01	110	− 16.80 (12.0)	0.17	0.38
	STS60	113	− 1.87 (0.9)	0.03	112	− 0.23 (0.8)	0.78	0.33
NT pro-BNP (pg/ml) b	ISWT	108	− 22.83 (10.0)	0.02	107	− 20.33 (8.9)	0.02	0.39
	STS60	110	− 1.24 (0.7)	0.06	109	− 1.34 (0.6)	0.03	0.35
LVMi (g/m2)	ISWT	114	0.86 (0.8)	0.28	113	− 0.31 (0.7)	0.67	0.39
	STS60	117	0.04 (0.1)	0.46	116	− 0.03 (0.05)	0.52	0.34
LV ejection fraction (%)	ISWT	114	3.18 (1.6)	0.06	113	3.74 (1.4)	0.01	0.43
	STS60	117	0.15 (0.1)	0.16	116	0.14 (0.1)	0.15	0.35
PWV (m/s)	ISWT	103	− 9.72 (3.2)	< 0.01	102	− 1.10 (3.2)	0.74	0.39
	STS60	106	− 0.47 (0.2)	0.04	105	0.11 (0.2)	0.64	0.33
LV mass:volume (g/mL)	ISWT	114	− 50.70 (99.7)	0.61	113	− 46.93 (82.9)	0.57	0.39
	STS60	117	− 1.27 (6.6)	0.85	116	− 0.45 (5.7)	0.94	0.33
Global Native T1 (ms)	ISWT	109	− 1.45 (0.4)	< 0.01	108	− 1.29 (0.3)	< 0.01	0.48
	STS60	112	− 0.07 (0.03)	0.01	111	− 0.06 (0.02)	0.02	0.36
Global longitudinal strain (%)	ISWT	114	− 8.20 (5.0)	0.10	116	− 7.97 (4.3)	0.07	0.41
	STS60	117	− 0.48 (0.3)	0.13	112	− 0.27 (0.3)	0.34	0.34

The reference category for gender is ‘male’, for history of diabetes is ‘no’ and for ethnicity is ‘white’

BMI body mass index, LVMi left ventricular mass index, LV left ventricle, PWV pulse wave velocity, ISWT incremental shuttle walk test, STS60 sit-to-stand 60

^aadjusted for age, gender, BMI, diabetic status, ethnicity and systolic blood pressure

^bLog transformed data. B = unstandardized beta coefficient; SE = standard error of the mean