Table 2.
Predictors of events during follow-up at univariate Cox analysis
| HR | 95% CI | p | |
|---|---|---|---|
| Age (years) | 1.082 | 1.034–1.133 | 0.001 |
| Male sex | 2.346 | 0.783–7.033 | 0.128 |
| BMI (Kg/m2) | 1.019 | 0.938–1.107 | 0.656 |
| eGFR (mL/min/1.73 m2) | 0.978 | 0.961–0.996 | 0.016 |
| Heart rate (b/min) | 0.989 | 0.943–1.037 | 0.647 |
| SBP (mmHg) | 1.008 | 0.974–1.043 | 0.668 |
| DBP (mmHg) | 1.010 | 0.967–1.054 | 0.657 |
| hs-TnI (pg/mL) | 1.002 | 1.001–1.004 | 0.031 |
| NT-proBNP (pg/mL) | 1.001 | 1.001–1.002 | 0.002 |
| LV hypertrophy | 13.805 | 1.802–105.750 | 0.012 |
| LV mass index (g/m2.7) | 1.022 | 1.008–1.036 | 0.002 |
| Left atrium volume (mL/m2) | 1.028 | 1.011–1.045 | 0.001 |
| E/Ea ratio | 1.162 | 1.082–1.248 | < 0.001 |
| LV EDVi (mL/m2) | 1.006 | 0.974–1.038 | 0.730 |
| LV ESVi (mL/m2) | 1.021 | 0.993–1.048 | 0.139 |
| LV ejection fraction (%) | 0.926 | 0.873–0.984 | 0.012 |
| Global longitudinal strain (%) | 1.309 | 1.124–1.525 | 0.001 |
| MEE index (mL/s per g) | 0.906 | 0.849–0.965 | 0.002 |
| GWI (mmHg%) | 0.998 | 0.997–0.999 | < 0.001 |
| GCW (mmHg%) | 0.998 | 0.997–0.999 | < 0.001 |
| GWW (mmHg%) | 1.006 | 1.003–1.009 | < 0.001 |
| GWE (%) | 0.897 | 0.854–0.943 | < 0.001 |
HR hazard ratio, CI confidence interval, eGFR estimated glomerular filtration rate, hs-TnI high-sensitivity troponin I, NT-proBNP N-terminal prohormone of Brain Natriuretic Peptide, LV left ventricular, E/Ea ratio the ratio of mitral (E) to mitral annulus (Ea) early diastolic peak velocity, EDVi end-diastolic volume indexed to body surface area, ESVi end-systolic volume indexed to body surface area, MEE mechano-energetic efficiency, GWI global work index, GCW global constructive work, GWW global wasted work, GWE global work efficiency