. Author manuscript; available in PMC: 2021 Apr 8.

Published in final edited form as: Lupus. 2021 Jan 28;30(5):741–751. doi: 10.1177/0961203321989803

TABLE 4:

COMPOSITE DELIVERY OUTCOMES

PREGNANCY PLANNING ¹	Overall N=35	Not-planned n=15	Planned n=20	p-value
PROMISSE-APO²	20/33 (61%)	11/14 (79%)	9/19 (47%)	0.09
Severe PROMISSE-APO³	6/33 (18%)	6/14 (43%)	0/19 (0%)	0.003
Severe Neonatal Outcome⁴	13/29 (45%)	7/10 (70%)	6/19 (32%)	0.06
PRE-PREGNANCY LUPUS ACTIVITY¹	Overall N=35	PGA ≥ 1.5 n=6	PGA < 1.5 n=29	p-value
PROMISSE-APO²	20/33 (61%)	5/5 (100%)	15/28 (54%)	0.1
Severe PROMISSE-APO³	6/33 (18%)	3/5 (60%)	3/28(11%)	0.03
Severe Neonatal Outcome⁴	13/29 (45%)	4/4 (100%)	9/25 (36%)	0.03
MATERNAL RACE⁵	Overall N=35	Black n=15	White or Other n=20	p-value
PROMISSE-APO²	20/33 (61%)	10/14 (71%)	10/19 (53%)	0.3
Severe PROMISSE-APO³	6/33 (18%)	4/14 (29%)	2/19(11%)	0.4
Severe Neonatal Outcome⁴	13/29 (45%)	6/11 (55%)	7/18 (39%)	0.5

^1.

Delivery outcomes missing: 8 pregnancies; not delivered as of 4/1/2020 (n=7) or data was unavailable (n=1).

^2.

PROMISSE-APO: neonatal death, fetal death > 12 weeks, preeclampsia, preterm delivery < 36 weeks, or small for gestational age (SGA) < 5th percentile. Pregnancy losses < 12 weeks were excluded.¹⁰

^3.

Severe PROMISSE-APO: neonatal death, fetal death > 12 weeks, preeclampsia and preterm delivery < 34 weeks, or preterm delivery < 30 weeks. Pregnancy losses < 12 weeks were excluded.¹⁰

^4.

Severe neonatal outcomes among live births: neonatal death, NICU stay > 1 week, APGAR < 7 at 5 minutes, or SGA < 5th percentile.

^5.

For composite delivery outcomes by demographics, see Supplemental Table 2.