Combined USP18, ATGL and UCP1 expression profiles in human lung cancers were interrogated using TCGA database. (A) Comparisons of USP18, ATGL and UCP1 mRNA levels were between normal and malignant (adenocarcinoma, AD, and squamous cell carcinoma, SCC) lung tissues using the TCGA database. (B) Kaplan-Meier analysis of survival in human lung adenocarcinomas and squamous cell carcinomas are displayed. Cases with higher combined USP18, ATGL and UCP1 expression levels had an unfavorable survival as compared to those cases with lower USP18, ATGL and UCP1 expression profiles, as shown in this panel.