Table 7.

Results of the nonparametric voxel-based morphometry (VBM) analysis comparing DK’s gray matter maps at each time point to a control group (N=76). The Table shows significant clusters at a cluster-level threshold of p<.001, FWE-corrected (p<.05), with labels derived from Harvard-Oxford atlas (Desikan et al., 2006).

Pre- Passive Treatment								Post- Passive Treatment
Cluster Size	Pseudo-t	Peak coordinates			Peak Region	Extent	L/R	Cluster Size	Pseudo-t	Peak coordinates			Peak Region	Extent	L/R
		x	y	z						x	y	z
557	5.92	−30	2	−20	Amygdala	Hippocampus, Parahippocampal anterior	L	758	6.85	−29	0	−18	Amygdala	Hippocampus, Parahippocampal anterior, Insula, Temporal Pole	L
Pre- Cleft Treatment								Post- Cleft Treatment
Cluster Size	Pseudo-t	Peak coordinates			Peak Region	Extent	L/R	Cluster Size	Pseudo-t	Peak coordinates			Peak Region	Extent	L/R
		x	y	z						x	y	z
1899	6.85	−26	−10	−24	Hippocampus	Parahippocampal anterior, Temporal Pole, Caudate, Insula, Amygdala, Putamen, Accumbens, Planum Polare	L	1663	7.58	−26	−6	−21	Amygdala	Hippocampus, Parahippocampal anterior, Putamen, Accumbens, Insula, Temporal Pole, Temporal Fusiform anterior, Planum Polare	L
								240	5.63	−14	12	12	Caudate	Accumbens	L
								467	5.14	27	−4	−24	Amygdala	Hippocampus, Parahippocampal anterior, Temporal Pole	R