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. Author manuscript; available in PMC: 2022 Feb 15.
Published in final edited form as: J Neurosci Methods. 2020 Dec 3;350:109018. doi: 10.1016/j.jneumeth.2020.109018

Fig. B.2. The bias of diffusivity parallel to membranes due to rejection sampling.

Fig. B.2.

The algorithm of rejecting steps toward a membrane due to rejection sampling causes the bias in diffusivity D∥ parallel to the membrane (e.g., two parallel planes in 3d). This bias is roughly proportional to the step size δs and closely related to the surface-to-volume ratio S/V of the geometry.