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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Clin Cancer Res. 2021 Feb 4;27(7):2038–2049. doi: 10.1158/1078-0432.CCR-20-3262

Figure 4-. Patient cohort validates that tumor volume negatively correlates with lymphocytes prior to surgery and steroid treatment.

Figure 4-

Using a cohort of n=95 patients prior to surgical resection, the first CBC with differential was used to compare % lymphocytes between dexamethasone-treated- and non-dexamethasone-treated patients (A). Percentages of lymphocytes vs tumor volumes (assessed by MRI) of patients without dexamethasone treatment (B). Percentages of lymphocytes vs tumor volumes for those patients treated with dexamethasone prior to surgery who also had a matching MRI at the time of CBC w/ diff (C). Multivariate Cox proportional hazards model of Progression Free Survival (D). Multivariable Cox proportional hazards model of Overall survival (E). Absolute lymphocyte counts at recurrence and pre-op are correlated for patients not treated with steroids at the time of pre op absolute lymphocyte count (F). The correlation coefficient (R), p value and fitted line parameter are shown.