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. Author manuscript; available in PMC: 2022 Apr 1.
Published in final edited form as: Cell Stem Cell. 2021 Feb 3;28(4):685–701.e7. doi: 10.1016/j.stem.2020.12.008

Figure 2. Depot-dependent regulation of fibrogenic and adipogenic gene programs in WAT PDGFRβ+ cells.

Figure 2.

(A) mRNA levels of indicated adipogenesis (top)- and fibrosis (bottom) -related genes within freshly isolated gWAT APCs and FIPs from chow-fed mice or aged-matched animals maintained on HFD for 10 weeks.

(B) mRNA levels of indicated adipogenesis (top)- and fibrosis (bottom) -related genes within freshly isolated iWAT DPP4− PDGFRβ+ and DPP4+ PDGFRβ+ cells from chow-fed mice or aged-matched animals maintained on HFD for 10 weeks.

Bars represent mean + s.e.m. * denotes p< 0.05 by two-way ANOVA.

Each sample (n) represents 10,000 freshly isolated cells from 2-3 individual depots. n=6 for HFD FIPs. n=4 for all other subpopulations analyzed.