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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Cell Signal. 2021 Feb 11;82:109947. doi: 10.1016/j.cellsig.2021.109947

Figure 15. Prenylation and post prenylation processing at the CAAX motif in Gγ.

Figure 15.

Farnesyl or geranylgeranyl moieties are transferred to the carboxy terminus of Gγ from FPP and GGPP with the aid of either farnesyl or geranylgeranyl transferases, respectively. The last three amino acids are subsequently cleaved off from the CAAX motif by RCE1 and is followed by a methyl group addition to the new C terminus. GGPP: Geranylgeranyl pyrophosphate, FPP: Farnesyl pyrophosphate, PPi: Pyrophosphate.