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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Cell Signal. 2021 Feb 11;82:109947. doi: 10.1016/j.cellsig.2021.109947

Table 10:

Pre-CAAX regions of all 12 Gγ subunits, their translocation Tt½ times and PM affinities [48].

Pre-CAAX Tt½ (s) PM affinity
Gγ9 NPFKE-KGGC-far 5 ± 1 Low affinity
Gγ1 NPFKELKGGC-far 13 ± 2
Gγ11 NPFKE-KGSC-far 38 ± 2
Gγ7 NPFKDKKP-C-gerger 41 ± 2
Gγ5 NPFRPQKV-C-gerger 71 ± 3 Moderate affinity
Gγ12 NPFKDKKT-C-gerger 80 ± 2
Gγ10 NPFREPRS-C-gerger 97 ± 4
Gγ13 NPWVE-KGKC-gerger 100 ± 3
Gγ4 NPFREKKFFC-gerger 116 ± 2
Gγ8 NPFRDKRLFC-gerger 124 ± 1
Gγ2 NPFREKKFFC-gerger 181 ± 4 High affinity
Gγ3 NPFREKKFFC-gerger 270 ± 4