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. Author manuscript; available in PMC: 2022 Apr 15.
Published in final edited form as: J Immunol. 2021 Mar 31;206(8):1776–1783. doi: 10.4049/jimmunol.2000051

Figure 4. Constitutive activation of canonical NF-κB in Treg cells rescues the inflammatory phenotype in Pdk1-deficient mice.

Figure 4.

Foxp3YFP-cre Pdk1f/f mice were crossed to R26-StopFLikk2ca (Ikk2ca) mice. H&E staining of lung and liver sections from 3-week old mice. Bars=100μm; original magnification: 100X. (B,C) Representative H&E staining (B) and cumulative ear thickness of 3-week old mice of the indicated genotypes (C, Mean +/− S.D. is shown). (D) Inflammatory features in the lung, skin and liver of each genotype, as described in the Methods section. Data is representative or cumulative of five mice per group from five experiments. **p<0.005.