A. Ghrelin attenuates the up-regulation of hepatic PPAR-γ induced by low dose of LPS (240μg/kg/day) in mice fed NCD or HFD.
B. Ghrelin attenuates the up-regulation of hepatic CD36 induced by low dose of LPS (240μg/kg/day) in mice fed NCD or HFD.
C. No effects of ghrelin and LPS on lipid accumulation in hepatocytes treated with or without Kupffer cells/macrophages supernatants in the condition of PPAR-γ deficiency. n=5. Both Kupffer cells/macrophages and hepatocytes were isolated from PPAR-γ+/− mice.
n=5–6 each unless indicated otherwise. * denotes P<0.05 vs control.