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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Neurobiol Dis. 2021 Feb 24;153:105318. doi: 10.1016/j.nbd.2021.105318

Fig. 7. Oral GTB prevents microglial NF-κB activation in HD mice.

Fig. 7.

NF-κB activation in microglia of different groups of experimental mice was monitored by evaluating the expression of phospho-Ser 536 form of p65. Immunofluorescence analysis was performed to visualize the expression of phospho-Ser 536 p65 in Iba1 positive microglia in both striatum (A) and cortex (C). Images are shown in 20X magnification and further zoomed to shown individual microglia. Two sections from each brain were taken for the immunostaining and the MFI value of phospho-p65 obtained from each section is presented in the diagram. One-way ANOVA followed by Tukey’s multiple comparison tests was performed for statistical analyses. ***p< 0.001 indicates statistical significance compared to respective groups. Results are represented as mean ± SEM (n=5).