Table 1.
Characteristics of the Study Participants by Quartile of Percent Emphysema.
| Percent emphysema (−950 HU) | ||||
|---|---|---|---|---|
| 1st Quartile | 2nd Quartile | 3rd Quartile | 4th Quartile | |
| n=79 | n=79 | n=79 | n=78 | |
| Demographics | ||||
| Age, mean ± SD, years | 66 ± 7 | 69 ± 6 | 68 ± 7 | 69 ± 7 |
| Male, N (%) | 36 (46) | 44 (56) | 53 (67) | 55 (70) |
| Race/Ethnicity, N (%) | ||||
| White | 34 (43) | 39 (49) | 46 (58) | 50 (64) |
| Chinese | 7 (9) | 3 (4) | 6 (8) | 3 (4) |
| African-American | 24 (30) | 22 (28) | 17 (21) | 20 (26) |
| Hispanic | 14 (18) | 15 (19) | 10 (13) | 5 (6) |
| Educational attainment, N (%) | ||||
| ≤ High school degree | 24 (30) | 12 (24) | 16 (20) | 17 (22) |
| Some college/Assoc. degree/Vocational school | 25 (32) | 20 (25) | 27 (34) | 20 (26) |
| ≥ College degree | 30 (38) | 40 (51) | 36 (45) | 41 (52) |
| Hypertension, N (%) | 36 (46) | 33 (42) | 40 (51) | 36 (46) |
| Diabetes Mellitus, N (%) | 12 (15) | 12 (15) | 11 (14) | 10 (13) |
| Smoking status, N (%) | ||||
| Current | 29 (37) | 19 (24) | 19 (24) | 21 (27) |
| Former | 50 (63) | 60 (76) | 60 (76) | 57 (73) |
| Pack-years of smoking, median [IQR] | 32 [20–46] | 32 [22–48] | 32 [19–51] | 33 [20–52] |
| Characteristics | ||||
| Height, mean ± SD, cm | 165 ± 10 | 168 ± 10 | 170 ± 8 | 171 ± 9 |
| Weight, mean ± SD, kg | 78 ± 17 | 83 ± 18 | 80 ± 16 | 78 ± 18 |
| Body mass index, mean ± SD, kg/m2 | 28 ± 5 | 29 ± 5 | 28 ± 5 | 27 ± 5 |
| Body surface area, mean ± SD, m2 | 1.8 ± 0.22 | 1.9 ± 0.23 | 1.9 ± 0.20 | 1.9 ± 0.23 |
| Systolic blood pressure, mean ± SD, mmHg | 122 ± 17 | 121 ± 18 | 121 ± 20 | 122 ± 15 |
| Diastolic blood pressure, mean ± SD, mmHg | 70 ± 10 | 69 ± 9 | 69 ± 10 | 72 ± 8 |
| MAP, mean ± SD, mmHg | 87 ± 11 | 86 ± 10 | 87 ± 12 | 89 ± 9 |
| PP, mean ± SD, mmHg | 51 ± 15 | 52 ± 15 | 52 ± 15 | 49 ± 13 |
| Labs | ||||
| Cotinine levels, mean ± SD, mg/dL | 133 ± 211 | 360 ± 2245 | 88 ± 180 | 139 ± 647 |
| LDL, mean ± SD, mg/dL | 106 ± 31 | 109 ± 32 | 110 ± 32 | 97 ± 31 |
| HDL, mean ± SD, mg/dL | 58 ± 20 | 54 ± 16 | 58 ± 19 | 56 ± 18 |
| Triglycerides, mean ± SD, mg/dL | 101 ± 44 | 112 ± 50 | 109 ± 43 | 120 ± 84 |
| Cholesterol, median [IQR] | 178 [160–205] | 182 [159–210] | 187 [160–222] | 178 [147–196] |
| Pulmonary function test | ||||
| FEV1 percent of predicted, mean ± SD | 91 ± 17 | 95 ± 20 | 92 ± 17 | 75 ± 25 |
| FVC percent of predicted, mean ± SD | 92 ± 13 | 97 ± 14 | 101 ± 16 | 97 ± 18 |
| FEV1/FVC ratio, mean ± SD | 0.75 ± 0.09 | 0.73 ± 0.08 | 0.69 ± 0.1 | 0.56 ± 0.14 |
Definition of abbreviations: FVC = forced vital capacity; FEV1= forced expiratory volume in 1 second; IQR = interquartile range; MAP = Mean Arterial Pressure; Percent emphysema (−950 HU) = percentage of emphysema-like lung at −950 Hounsfield units; PP = Pulse Pressure.