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. Author manuscript; available in PMC: 2021 Oct 15.
Published in final edited form as: J Immunol. 2021 Mar 24;206(8):1719–1728. doi: 10.4049/jimmunol.2001266

Figure 1. PPP2R2A expression is increased in T cells from patients with SLE and correlates with ROCK activity.

Figure 1.

(A) Western blot showing PPP2R2A expression in T cells from healthy donors and SLE patients. H: Healthy donors; L: Lupus patients. (B) Quantification of PPP2R2A expression in T cells from healthy donors and SLE patients. Healthy donors: n=11; SLE patients: n=15. (C) Western blot showing p-MYPT1 expression in T cells from healthy donors and SLE patients. (D) Quantification of p-MYPT in T cells from healthy donors and SLE patients. Healthy donors: n=7; SLE patients: n=10. (E) Correlation between expression levels of PPP2R2A and pMYPT1 from T cells from healthy donors (filled dots, n=7) and patients with SLE (open dots, n=10). HC: Healthy controls. *P<0.05 by unpaired t test with Welch’s correction. The samples were collected from three independent times.