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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Cancer Prev Res (Phila). 2021 Jan 28;14(4):433–440. doi: 10.1158/1940-6207.CAPR-20-0448

Figure 1.

Figure 1.

Map of ATM and all variants discovered in this study. This map shows the types and frequency of ATM variants discovered within this patient cohort. The circle size/line length reflects the number of times a variant was observed at that location. The exons are numbered, with in-frame exons being dark blue and out-of-frame exons being grey. The untranslated region (UTR) is reflected in light blue. The functional regions of the gene are also shown. Tan: Tel1/ATM N-Terminal motif; NLS: nuclear localization sequence; LZ: leucine zipper; Prch: Proline rich; FAT: FRAP, ATM, TRRAP motif; CS: ZCatalytic site; PTS1: yPeroxisomal targeting signal sequence.