Table 2.
Summary of aTRV and ICC values for VT estimates by 2TCM-c and Logan
| Brain region | 2TCM-c VT (mL/cm3) | Logan (t* = 60) VT (mL/cm3) | ||
|---|---|---|---|---|
| aTRV | ICC | aTRV | ICC | |
| Striatum | 12% | 0,52 | 11% | 0.67 |
| Thalamus | 18% | 0,05 | 12% | 0.61 |
| Cerebellum | NA | NA | 14% | 0.32 |
| White matter | 24% | 0.43 | 13% | 0.62 |
| Frontal cortex | 11% | 0.84 | 11% | 0.89 |
| Temporal cortex | 25% | NA | 13% | 0.61 |
| Parietal cortex | 19% | 0.38 | 12% | 0.75 |
aTRV and ICC calculation of the most relevant VT estimates obtained with 2TCM-c and Logan. Only estimates at <25%SE were included. For 2TCM, only NHP2 had acceptable estimates in both test-, and retest conditions.