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. 2020 Jul 9;42(3):393–403. doi: 10.1038/s41401-020-0461-z

Fig. 3. Zonisamide mitigates apoptosis in diabetic hearts.

Fig. 3

a, b TUNEL assay results and quantification of cell apoptosis in the Con, T2DM, and T2DM + ZNS groups (green, TUNEL staining; blue, DAPI staining). c–f Western blotting results and quantitative analysis of Bcl-2, Bax, caspase-3, and cleaved caspase-3 expression. All values are the fold changes normalized to their control group. The data are presented as the means ± SEM (n = 4-5). *P < 0.05, **P < 0.01 vs. Con; #P < 0.05, ##P < 0.01 vs. T2DM.