Table 1.

Potential serum metabolic biomarkers identified for high myopia.

ID	Metabolite	VIP	P value	Fold change	AUC
1	Alanine	1.61	2.31E−3	0.72	0.71
2	Citric acid	1.66	6.66E−3	1.25	0.69
3	Aminomalonic acid	1.27	1.61E−2	1.36	0.65
4	Mannose	2.09	1.48E−2	0.50	0.65
5	Palmitoleic acid	1.10	9.91E−3	1.59	0.64
6	Conduritol b epoxide	1.76	5.36E−3	1.31	0.71
7	Shikimic acid	1.51	3.81E−3	1.49	0.70
8	Itaconic acid	1.69	1.74E−2	0.45	0.67
9	4-Hydroxyphenylacetic acid	1.20	3.99E−2	1.60	0.59
10	Aconitic acid	1.96	2.34E−2	0.49	0.64
11	O-Acetylserine	1.66	9.28E−3	0.46	0.68
12	Hesperitin	2.49	8.94E−3	1.78	0.63
13	Phthalic acid	1.25	3.11E−3	0.71	0.68
14	Abietic acid	1.02	4.34E−2	0.61	0.64
15	Anandamide	1.79	1.46E−2	1.98	0.61
16	Oxalacetic acid	1.66	3.91E−2	1.24	0.60
17	Salicin	1.82	2.45E−2	0.57	0.64
18	Pimelic acid	1.69	3.67E−3	2.41	0.63
19	2-Ketoadipate	2.02	2.46E−2	1.94	0.64
20	N-Ethylmaleamic acid	1.40	4.86E−2	1.20	0.62

VIP variable importance in the projection, AUC area under the receiver operating characteristic curve.