Table 3.

Rescue treatment and clinical outcome of patients with HLA-loss and classical relapses of post-transplantation.

		HLA-loss relapse		Classical relapse
		Retrospective	Prospective
Number of patients (n)		4	2	16
Patient ID#		1–4	5,6	7–22
Treatment at relapse	No treatment	1	-	2
	Chemotherapy	-	2	9
	DLIs	-	-	1
	DLIs plus chemotherapy	3	-	4
Severe GVHD after rescue treatment		3	-	3
OS	At 6 months	50%	100%	31%
	At 1 year	25%	50%	18%

Detailed information on the rescue treatments used and on the clinical outcome is provided in Supplementary Table 2. Severe GVHD includes III-IV aGVHD and cGVHD. DLIs, donor lymphocyte infusions; GVHD, graft-vs.-host disease; OS, overall survival.