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. 2021 Apr 7;11:7653. doi: 10.1038/s41598-021-86986-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Binding analyses of lead CTL epitope with host membrane specific TLR2 receptor (A) Interacting complex of lead CTL epitope with TLR2, mesh network, TLR2 residues shown in sky blue and CTL epitope in orange color. (B) Molecular interactions involved in the strong binding of lead CTL epitope to TLR2 receptor. (C) Surface view of a binding grove of TLR2 during interaction of CTL epitope. (D) CTL epitope binding cavity network responsible strong and stable binding with TLR2.